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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC1DNA excision repair protein ERCC-1 isoform X1. (405 aa)    
Predicted Functional Partners:
ERCC4
DNA repair endonuclease XPF isoform X1.
   
 0.999
FANCM
Fanconi anemia group M protein.
   
 0.997
XPA
DNA repair protein complementing XP-A cells isoform X1.
    
 0.985
SLX4
Structure-specific endonuclease subunit SLX4.
   
 0.951
FANCL
E3 ubiquitin-protein ligase FANCL.
    
 0.918
MUS81
Crossover junction endonuclease MUS81 isoform X2.
   
 0.915
FANCG
Fanconi anemia group G protein.
    
 0.893
FANCB
Fanconi anemia group B protein.
    
 0.884
EME1
Crossover junction endonuclease EME1.
    
 0.844
SLX1A
SLX1 homolog A, structure-specific endonuclease subunit.
   
 0.820
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.