close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF4Tumor necrosis factor receptor superfamily member 4. (270 aa)    
Predicted Functional Partners:
TNFSF4
Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family.
    
 0.991
TNFRSF18
Tumor necrosis factor receptor superfamily member 18.
   
  
0.798
TIGIT
T-cell immunoreceptor with Ig and ITIM domains.
      
 0.716
IL12RB2
Interleukin-12 receptor subunit beta-2.
      
 0.697
TNFRSF9
Tumor necrosis factor receptor superfamily member 9 isoform X2.
   
 
0.656
VSIR
V-type immunoglobulin domain-containing suppressor of T-cell activation.
      
 0.607
LAG3
Lymphocyte activation gene 3 protein isoform X1.
   
 
 0.555
CTLA4
Cytotoxic T-lymphocyte protein 4 isoform X1.
   
  
 0.546
FCGRT
IgG receptor FcRn large subunit p51 isoform X2; Belongs to the MHC class I family.
      
 0.544
ITGAE
Integrin alpha-E; Belongs to the integrin alpha chain family.
   
  
 0.542
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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