UBE2J2 protein (Vulpes vulpes) - STRING interaction network

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UBE2J2

Ubiquitin-conjugating enzyme E2 J2. (259 aa)

Predicted Functional Partners:

UBE2V1

0.842

MARCHF6

0.804

DERL2

0.799

UBE2G2

0.771

UBE2W

0.770

LMAN2

0.765

MOGS

0.745

UBE2O

0.740

ATG7

0.724

UBE2S

0.719

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG7	UBE2G2	ENSVVUP00000021352	ENSVVUP00000033082	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.	0.691
ATG7	UBE2J2	ENSVVUP00000021352	ENSVVUP00000005335	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-conjugating enzyme E2 J2.	0.724
ATG7	UBE2O	ENSVVUP00000021352	ENSVVUP00000020573	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	(E3-independent) E2 ubiquitin-conjugating enzyme isoform X1.	0.632
ATG7	UBE2S	ENSVVUP00000021352	ENSVVUP00000009616	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family.	0.635
ATG7	UBE2V1	ENSVVUP00000021352	ENSVVUP00000030702	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-conjugating enzyme E2 variant 1 isoform X3.	0.830
ATG7	UBE2W	ENSVVUP00000021352	ENSVVUP00000026510	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-conjugating enzyme E2 W.	0.694
DERL2	LMAN2	ENSVVUP00000038310	ENSVVUP00000000045	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Vesicular integral-membrane protein VIP36 isoform X1.	0.708
DERL2	MARCHF6	ENSVVUP00000038310	ENSVVUP00000024374	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	E3 ubiquitin-protein ligase MARCH6.	0.465
DERL2	MOGS	ENSVVUP00000038310	ENSVVUP00000005711	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Mannosyl-oligosaccharide glucosidase.	0.611
DERL2	UBE2G2	ENSVVUP00000038310	ENSVVUP00000033082	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.	0.506
DERL2	UBE2J2	ENSVVUP00000038310	ENSVVUP00000005335	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2 J2.	0.799
LMAN2	DERL2	ENSVVUP00000000045	ENSVVUP00000038310	Vesicular integral-membrane protein VIP36 isoform X1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.708
LMAN2	MOGS	ENSVVUP00000000045	ENSVVUP00000005711	Vesicular integral-membrane protein VIP36 isoform X1.	Mannosyl-oligosaccharide glucosidase.	0.775
LMAN2	UBE2J2	ENSVVUP00000000045	ENSVVUP00000005335	Vesicular integral-membrane protein VIP36 isoform X1.	Ubiquitin-conjugating enzyme E2 J2.	0.765
MARCHF6	DERL2	ENSVVUP00000024374	ENSVVUP00000038310	E3 ubiquitin-protein ligase MARCH6.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.465
MARCHF6	UBE2G2	ENSVVUP00000024374	ENSVVUP00000033082	E3 ubiquitin-protein ligase MARCH6.	Ubiquitin-conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.	0.824
MARCHF6	UBE2J2	ENSVVUP00000024374	ENSVVUP00000005335	E3 ubiquitin-protein ligase MARCH6.	Ubiquitin-conjugating enzyme E2 J2.	0.804
MOGS	DERL2	ENSVVUP00000005711	ENSVVUP00000038310	Mannosyl-oligosaccharide glucosidase.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.611
MOGS	LMAN2	ENSVVUP00000005711	ENSVVUP00000000045	Mannosyl-oligosaccharide glucosidase.	Vesicular integral-membrane protein VIP36 isoform X1.	0.775
MOGS	UBE2J2	ENSVVUP00000005711	ENSVVUP00000005335	Mannosyl-oligosaccharide glucosidase.	Ubiquitin-conjugating enzyme E2 J2.	0.745