MYRF protein (Vulpes vulpes) - STRING interaction network

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MYRF

Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (1323 aa)

Predicted Functional Partners:

OLIG2

0.765

PLP1

0.753

RFFL

0.751

MBP

0.742

PPP1R32

0.734

ENPP6

0.732

SOX10

0.607

PEX2

0.567

MAG

0.552

SPO11

0.548

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENPP6	MYRF	ENSVVUP00000017769	ENSVVUP00000005345	Ectonucleotide pyrophosphatase/phosphodiesterase family member 6.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.732
ENPP6	OLIG2	ENSVVUP00000017769	ENSVVUP00000031647	Ectonucleotide pyrophosphatase/phosphodiesterase family member 6.	Oligodendrocyte transcription factor 2.	0.520
ENPP6	SOX10	ENSVVUP00000017769	ENSVVUP00000033263	Ectonucleotide pyrophosphatase/phosphodiesterase family member 6.	Transcription factor SOX-10.	0.617
MAG	MBP	ENSVVUP00000020685	ENSVVUP00000025590	Myelin-associated glycoprotein isoform X1.	Myelin basic protein isoform X3.	0.801
MAG	MYRF	ENSVVUP00000020685	ENSVVUP00000005345	Myelin-associated glycoprotein isoform X1.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.552
MAG	OLIG2	ENSVVUP00000020685	ENSVVUP00000031647	Myelin-associated glycoprotein isoform X1.	Oligodendrocyte transcription factor 2.	0.624
MAG	PLP1	ENSVVUP00000020685	ENSVVUP00000001716	Myelin-associated glycoprotein isoform X1.	Myelin proteolipid protein isoform X1.	0.669
MAG	SOX10	ENSVVUP00000020685	ENSVVUP00000033263	Myelin-associated glycoprotein isoform X1.	Transcription factor SOX-10.	0.590
MBP	MAG	ENSVVUP00000025590	ENSVVUP00000020685	Myelin basic protein isoform X3.	Myelin-associated glycoprotein isoform X1.	0.801
MBP	MYRF	ENSVVUP00000025590	ENSVVUP00000005345	Myelin basic protein isoform X3.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.742
MBP	OLIG2	ENSVVUP00000025590	ENSVVUP00000031647	Myelin basic protein isoform X3.	Oligodendrocyte transcription factor 2.	0.824
MBP	PLP1	ENSVVUP00000025590	ENSVVUP00000001716	Myelin basic protein isoform X3.	Myelin proteolipid protein isoform X1.	0.807
MBP	SOX10	ENSVVUP00000025590	ENSVVUP00000033263	Myelin basic protein isoform X3.	Transcription factor SOX-10.	0.828
MYRF	ENPP6	ENSVVUP00000005345	ENSVVUP00000017769	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Ectonucleotide pyrophosphatase/phosphodiesterase family member 6.	0.732
MYRF	MAG	ENSVVUP00000005345	ENSVVUP00000020685	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Myelin-associated glycoprotein isoform X1.	0.552
MYRF	MBP	ENSVVUP00000005345	ENSVVUP00000025590	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Myelin basic protein isoform X3.	0.742
MYRF	OLIG2	ENSVVUP00000005345	ENSVVUP00000031647	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Oligodendrocyte transcription factor 2.	0.765
MYRF	PEX2	ENSVVUP00000005345	ENSVVUP00000021935	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Peroxisome biogenesis factor 2.	0.567
MYRF	PLP1	ENSVVUP00000005345	ENSVVUP00000001716	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Myelin proteolipid protein isoform X1.	0.753
MYRF	PPP1R32	ENSVVUP00000005345	ENSVVUP00000006324	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Protein phosphatase 1 regulatory subunit 32.	0.734

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