Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSVVUP00000005377annotation not available (72 aa)    
Predicted Functional Partners:
ABRAXAS1
BRCA1-A complex subunit Abraxas 1 isoform X1.
    
 0.661
BABAM1
BRISC and BRCA1-A complex member 1.
    
 0.648
BABAM2
BRISC and BRCA1-A complex member 2 isoform X2.
    
 0.630
LOC112908355
LOW QUALITY PROTEIN: lys-63-specific deubiquitinase BRCC36-like.
    
 0.599
BRCC3
Lys-63-specific deubiquitinase BRCC36.
    
 0.599
BARD1
BRCA1-associated RING domain protein 1.
    
 0.593
BRCA1
Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]
    
 0.565
ENSVVUP00000015370
annotation not available
  
     0.521
PAXIP1
PAX-interacting protein 1.
    
 0.465
MDC1
Mediator of DNA damage checkpoint protein 1 isoform X2.
    
 0.465
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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