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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JCHAINImmunoglobulin J chain. (159 aa)    
Predicted Functional Partners:
PIGR
Polymeric immunoglobulin receptor.
  
 0.994
ENSVVUP00000008525
annotation not available
   
 0.878
MZB1
Marginal zone B- and B1-cell-specific protein.
   
  
 0.830
FCMR
Fas apoptotic inhibitory molecule 3.
   
 0.798
IL2
Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.
    
 
 0.723
POU2AF1
POU domain class 2-associating factor 1.
   
  
 0.713
MIGA2
Mitoguardin 2 isoform X1.
      
 0.693
CD79B
B-cell antigen receptor complex-associated protein beta chain.
   
 
 0.683
CD79A
B-cell antigen receptor complex-associated protein alpha chain.
   
 
 0.680
TNFRSF17
LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 17.
   
  
 0.646
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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