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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENAMEnamelin. (1138 aa)    
Predicted Functional Partners:
AMTN
Amelotin.
  
   
 0.864
AMBN
Ameloblastin.
   
  
 0.823
ODAM
Odontogenic ameloblast-associated protein.
  
   
 0.807
KLK4
Kallikrein-4-like; Belongs to the peptidase S1 family.
      
 0.757
DMP1
Dentin matrix acidic phosphoprotein 1.
  
   
 0.738
MMP20
Matrix metalloproteinase-20.
   
  
 0.732
FAM20A
Pseudokinase FAM20A.
    
 0.689
MEPE
Matrix extracellular phosphoglycoprotein isoform X1.
  
   
 0.677
WDR72
WD repeat-containing protein 72.
      
 0.639
ENSVVUP00000002560
annotation not available
      
 0.609
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.