MAP1LC3A protein (Vulpes vulpes) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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Score

MAP1LC3A

LOW QUALITY PROTEIN: microtubule-associated proteins 1A/1B light chain 3A. (115 aa)

Predicted Functional Partners:

NBR1

0.981

FUNDC1

0.917

SQSTM1

0.899

ATG7

0.869

ATG4B

0.838

ATG3

0.823

KEAP1

0.805

ATG5

0.785

ATG12

0.778

ATG4A

0.771

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG3	ENSVVUP00000026693	ENSVVUP00000030097	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 3.	0.999
ATG12	ATG4A	ENSVVUP00000026693	ENSVVUP00000013591	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.734
ATG12	ATG4B	ENSVVUP00000026693	ENSVVUP00000031254	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.771
ATG12	ATG5	ENSVVUP00000026693	ENSVVUP00000005724	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG7	ENSVVUP00000026693	ENSVVUP00000021352	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.999
ATG12	FUNDC1	ENSVVUP00000026693	ENSVVUP00000016129	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	LOW QUALITY PROTEIN: FUN14 domain-containing protein 1.	0.621
ATG12	MAP1LC3A	ENSVVUP00000026693	ENSVVUP00000005619	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	LOW QUALITY PROTEIN: microtubule-associated proteins 1A/1B light chain 3A.	0.778
ATG12	NBR1	ENSVVUP00000026693	ENSVVUP00000033175	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Next to BRCA1 gene 1 protein isoform X1.	0.766
ATG12	SQSTM1	ENSVVUP00000026693	ENSVVUP00000002031	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Sequestosome-1.	0.820
ATG3	ATG12	ENSVVUP00000030097	ENSVVUP00000026693	Autophagy-related protein 3.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG3	ATG4A	ENSVVUP00000030097	ENSVVUP00000013591	Autophagy-related protein 3.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.805
ATG3	ATG4B	ENSVVUP00000030097	ENSVVUP00000031254	Autophagy-related protein 3.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.818
ATG3	ATG5	ENSVVUP00000030097	ENSVVUP00000005724	Autophagy-related protein 3.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.998
ATG3	ATG7	ENSVVUP00000030097	ENSVVUP00000021352	Autophagy-related protein 3.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.998
ATG3	MAP1LC3A	ENSVVUP00000030097	ENSVVUP00000005619	Autophagy-related protein 3.	LOW QUALITY PROTEIN: microtubule-associated proteins 1A/1B light chain 3A.	0.823
ATG3	NBR1	ENSVVUP00000030097	ENSVVUP00000033175	Autophagy-related protein 3.	Next to BRCA1 gene 1 protein isoform X1.	0.546
ATG3	SQSTM1	ENSVVUP00000030097	ENSVVUP00000002031	Autophagy-related protein 3.	Sequestosome-1.	0.595
ATG4A	ATG12	ENSVVUP00000013591	ENSVVUP00000026693	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.734
ATG4A	ATG3	ENSVVUP00000013591	ENSVVUP00000030097	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Autophagy-related protein 3.	0.805
ATG4A	ATG5	ENSVVUP00000013591	ENSVVUP00000005724	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.725