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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSTF2Cleavage stimulation factor subunit 2 isoform X3. (577 aa)    
Predicted Functional Partners:
CPSF3
Cleavage and polyadenylation specificity factor subunit 3 isoform X1.
   
 0.981
CSTF1
Cleavage stimulation factor subunit 1.
    
 0.978
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.978
SYMPK
Symplekin.
   
 0.977
CSTF3
Cleavage stimulation factor subunit 3.
   
 0.976
FIP1L1
pre-mRNA 3'-end-processing factor FIP1 isoform X1.
   
 0.968
CPSF1
Cleavage and polyadenylation specificity factor subunit 1.
   
 0.967
WDR33
pre-mRNA 3' end processing protein WDR33 isoform X1.
    
 0.945
PCF11
pre-mRNA cleavage complex 2 protein Pcf11 isoform X1.
    
 0.939
CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]
   
 0.926
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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