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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHPRHE3 ubiquitin-protein ligase SHPRH. (1722 aa)    
Predicted Functional Partners:
RAD18
E3 ubiquitin-protein ligase RAD18.
    
 0.832
PGM2
Phosphoglucomutase-2.
   
 
 0.808
MYSM1
Histone H2A deubiquitinase MYSM1 isoform X1.
   
 0.736
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.717
UBE2V2
Ubiquitin-conjugating enzyme E2 variant 2 isoform X1.
    
 0.705
FANCM
Fanconi anemia group M protein.
    
 0.684
UBE2V1
Ubiquitin-conjugating enzyme E2 variant 1 isoform X3.
    
 0.670
LOC112926351
Ubiquitin-conjugating enzyme E2 variant 1-like.
    
 0.662
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.659
SLCO1A2
Solute carrier organic anion transporter family member.
   
    0.653
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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