close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRGPRFMas-related G-protein coupled receptor member F; Belongs to the G-protein coupled receptor 1 family. (343 aa)    
Predicted Functional Partners:
CNN1
Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
   
    0.792
ZDHHC13
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.744
EFEMP2
EGF-containing fibulin-like extracellular matrix protein 2.
   
 0.626
PRRX2
Paired mesoderm homeobox protein 2.
    
 
 0.615
COPZ2
Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
     
 0.614
FKBP10
Peptidylprolyl isomerase.
      
 0.607
VGLL3
Transcription cofactor vestigial-like protein 3.
      
 0.559
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family.
   
  
 0.542
MAMDC2
MAM domain-containing protein 2.
    
 0.541
ATOH8
Protein atonal homolog 8.
      
 0.534
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (34%) [HD]