ACTL6A protein (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ACTL6A

Actin-like protein 6A isoform X1; Belongs to the actin family. (447 aa)

Predicted Functional Partners:

SMARCB1

0.985

PBRM1

0.980

ACTR8

0.973

PHF10

0.971

RUVBL1

0.969

SMARCD1

0.969

ARID4B

0.961

BRD7

0.961

ARID4A

0.961

SMARCA4

0.958

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTL6A	ACTR8	ENSVVUP00000006176	ENSVVUP00000028428	Actin-like protein 6A isoform X1; Belongs to the actin family.	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	0.973
ACTL6A	ARID4A	ENSVVUP00000006176	ENSVVUP00000041513	Actin-like protein 6A isoform X1; Belongs to the actin family.	AT-rich interactive domain-containing protein 4A isoform X1.	0.961
ACTL6A	ARID4B	ENSVVUP00000006176	ENSVVUP00000012273	Actin-like protein 6A isoform X1; Belongs to the actin family.	LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 4B.	0.961
ACTL6A	BRD7	ENSVVUP00000006176	ENSVVUP00000026336	Actin-like protein 6A isoform X1; Belongs to the actin family.	Bromodomain-containing protein 7 isoform X1.	0.961
ACTL6A	PBRM1	ENSVVUP00000006176	ENSVVUP00000036276	Actin-like protein 6A isoform X1; Belongs to the actin family.	Protein polybromo-1 isoform X5.	0.980
ACTL6A	PHF10	ENSVVUP00000006176	ENSVVUP00000009195	Actin-like protein 6A isoform X1; Belongs to the actin family.	PHD finger protein 10 isoform X1.	0.971
ACTL6A	RUVBL1	ENSVVUP00000006176	ENSVVUP00000025060	Actin-like protein 6A isoform X1; Belongs to the actin family.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.969
ACTL6A	SMARCA4	ENSVVUP00000006176	ENSVVUP00000024338	Actin-like protein 6A isoform X1; Belongs to the actin family.	Transcription activator BRG1 isoform X5.	0.958
ACTL6A	SMARCB1	ENSVVUP00000006176	ENSVVUP00000026505	Actin-like protein 6A isoform X1; Belongs to the actin family.	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.	0.985
ACTL6A	SMARCD1	ENSVVUP00000006176	ENSVVUP00000033950	Actin-like protein 6A isoform X1; Belongs to the actin family.	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D.	0.969
ACTR8	ACTL6A	ENSVVUP00000028428	ENSVVUP00000006176	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	Actin-like protein 6A isoform X1; Belongs to the actin family.	0.973
ACTR8	ARID4A	ENSVVUP00000028428	ENSVVUP00000041513	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	AT-rich interactive domain-containing protein 4A isoform X1.	0.467
ACTR8	ARID4B	ENSVVUP00000028428	ENSVVUP00000012273	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 4B.	0.467
ACTR8	PBRM1	ENSVVUP00000028428	ENSVVUP00000036276	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	Protein polybromo-1 isoform X5.	0.548
ACTR8	RUVBL1	ENSVVUP00000028428	ENSVVUP00000025060	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.996
ACTR8	SMARCB1	ENSVVUP00000028428	ENSVVUP00000026505	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.	0.557
ARID4A	ACTL6A	ENSVVUP00000041513	ENSVVUP00000006176	AT-rich interactive domain-containing protein 4A isoform X1.	Actin-like protein 6A isoform X1; Belongs to the actin family.	0.961
ARID4A	ACTR8	ENSVVUP00000041513	ENSVVUP00000028428	AT-rich interactive domain-containing protein 4A isoform X1.	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	0.467
ARID4A	ARID4B	ENSVVUP00000041513	ENSVVUP00000012273	AT-rich interactive domain-containing protein 4A isoform X1.	LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 4B.	0.575
ARID4A	PBRM1	ENSVVUP00000041513	ENSVVUP00000036276	AT-rich interactive domain-containing protein 4A isoform X1.	Protein polybromo-1 isoform X5.	0.735