NEFM protein (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NEFM

Neurofilament medium polypeptide; Belongs to the intermediate filament family. (967 aa)

Predicted Functional Partners:

KIF5A

0.918

KLC4

0.917

KLC2

0.916

KLC1

0.914

KLC3

0.914

KIF5B

0.912

KIF5C

0.912

NEFL

0.908

MAPK12

0.906

MAPK11

0.906

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KIF5A	KIF5B	ENSVVUP00000023405	ENSVVUP00000005912	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.960
KIF5A	KIF5C	ENSVVUP00000023405	ENSVVUP00000014994	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.946
KIF5A	KLC1	ENSVVUP00000023405	ENSVVUP00000000966	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 1 isoform X2.	0.996
KIF5A	KLC2	ENSVVUP00000023405	ENSVVUP00000037827	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 2.	0.991
KIF5A	KLC3	ENSVVUP00000023405	ENSVVUP00000005313	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 3 isoform X1.	0.978
KIF5A	KLC4	ENSVVUP00000023405	ENSVVUP00000039994	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 4.	0.991
KIF5A	NEFL	ENSVVUP00000023405	ENSVVUP00000006227	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Neurofilament light polypeptide; Belongs to the intermediate filament family.	0.933
KIF5A	NEFM	ENSVVUP00000023405	ENSVVUP00000006230	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Neurofilament medium polypeptide; Belongs to the intermediate filament family.	0.918
KIF5B	KIF5A	ENSVVUP00000005912	ENSVVUP00000023405	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.960
KIF5B	KIF5C	ENSVVUP00000005912	ENSVVUP00000014994	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.941
KIF5B	KLC1	ENSVVUP00000005912	ENSVVUP00000000966	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 1 isoform X2.	0.996
KIF5B	KLC2	ENSVVUP00000005912	ENSVVUP00000037827	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 2.	0.992
KIF5B	KLC3	ENSVVUP00000005912	ENSVVUP00000005313	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 3 isoform X1.	0.979
KIF5B	KLC4	ENSVVUP00000005912	ENSVVUP00000039994	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 4.	0.994
KIF5B	NEFL	ENSVVUP00000005912	ENSVVUP00000006227	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Neurofilament light polypeptide; Belongs to the intermediate filament family.	0.908
KIF5B	NEFM	ENSVVUP00000005912	ENSVVUP00000006230	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Neurofilament medium polypeptide; Belongs to the intermediate filament family.	0.912
KIF5C	KIF5A	ENSVVUP00000014994	ENSVVUP00000023405	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.946
KIF5C	KIF5B	ENSVVUP00000014994	ENSVVUP00000005912	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.941
KIF5C	KLC1	ENSVVUP00000014994	ENSVVUP00000000966	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 1 isoform X2.	0.991
KIF5C	KLC2	ENSVVUP00000014994	ENSVVUP00000037827	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin light chain 2.	0.995