close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYO1HUnconventional myosin-Ih; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1008 aa)    
Predicted Functional Partners:
BAZ1B
Tyrosine-protein kinase BAZ1B.
    
  0.604
MYO15A
Unconventional myosin-XV; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
 
  
 0.565
POLR1E
DNA-directed RNA polymerase I subunit RPA49 isoform X2.
    
  0.564
SF3B1
Splicing factor 3B subunit 1 isoform X1.
     
 0.562
DEK
Protein DEK.
     
 0.558
SMARCA1
Probable global transcription activator SNF2L1 isoform X3.
    
 0.531
SMARCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5.
    
 0.531
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.524
LOC112927180
Calmodulin-alpha-like.
    
 0.512
CALM3
Calmodulin-1; Belongs to the calmodulin family.
    
 0.512
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (36%) [HD]