PPP1R32 protein (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PPP1R32

Protein phosphatase 1 regulatory subunit 32. (429 aa)

Predicted Functional Partners:

SDHA

0.930

MYRF

0.734

TMEM98

0.724

PRSS56

0.609

C7orf57

0.579

BEST1

0.521

BEST3

0.521

FAM222A

0.516

CCDC181

0.516

ENSVVUP00000000110

0.477

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BEST1	PPP1R32	ENSVVUP00000004817	ENSVVUP00000006324	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Protein phosphatase 1 regulatory subunit 32.	0.521
BEST1	PRSS56	ENSVVUP00000004817	ENSVVUP00000035493	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Serine protease 56 isoform X2; Belongs to the peptidase S1 family.	0.450
BEST1	TMEM98	ENSVVUP00000004817	ENSVVUP00000028115	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Transmembrane protein 98.	0.502
BEST3	PPP1R32	ENSVVUP00000012092	ENSVVUP00000006324	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Protein phosphatase 1 regulatory subunit 32.	0.521
BEST3	PRSS56	ENSVVUP00000012092	ENSVVUP00000035493	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Serine protease 56 isoform X2; Belongs to the peptidase S1 family.	0.450
BEST3	TMEM98	ENSVVUP00000012092	ENSVVUP00000028115	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Transmembrane protein 98.	0.502
C7orf57	FAM222A	ENSVVUP00000014057	ENSVVUP00000005972	Uncharacterized protein C7orf57 homolog isoform X1.	Protein FAM222A.	0.516
C7orf57	PPP1R32	ENSVVUP00000014057	ENSVVUP00000006324	Uncharacterized protein C7orf57 homolog isoform X1.	Protein phosphatase 1 regulatory subunit 32.	0.579
CCDC181	PPP1R32	ENSVVUP00000036628	ENSVVUP00000006324	Coiled-coil domain-containing protein 181 isoform X1.	Protein phosphatase 1 regulatory subunit 32.	0.516
ENSVVUP00000000110	PPP1R32	ENSVVUP00000000110	ENSVVUP00000006324	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial-like.	Protein phosphatase 1 regulatory subunit 32.	0.477
ENSVVUP00000000110	SDHA	ENSVVUP00000000110	ENSVVUP00000030147	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial-like.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.999
FAM222A	C7orf57	ENSVVUP00000005972	ENSVVUP00000014057	Protein FAM222A.	Uncharacterized protein C7orf57 homolog isoform X1.	0.516
FAM222A	PPP1R32	ENSVVUP00000005972	ENSVVUP00000006324	Protein FAM222A.	Protein phosphatase 1 regulatory subunit 32.	0.516
MYRF	PPP1R32	ENSVVUP00000005345	ENSVVUP00000006324	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Protein phosphatase 1 regulatory subunit 32.	0.734
MYRF	TMEM98	ENSVVUP00000005345	ENSVVUP00000028115	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Transmembrane protein 98.	0.518
PPP1R32	BEST1	ENSVVUP00000006324	ENSVVUP00000004817	Protein phosphatase 1 regulatory subunit 32.	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	0.521
PPP1R32	BEST3	ENSVVUP00000006324	ENSVVUP00000012092	Protein phosphatase 1 regulatory subunit 32.	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	0.521
PPP1R32	C7orf57	ENSVVUP00000006324	ENSVVUP00000014057	Protein phosphatase 1 regulatory subunit 32.	Uncharacterized protein C7orf57 homolog isoform X1.	0.579
PPP1R32	CCDC181	ENSVVUP00000006324	ENSVVUP00000036628	Protein phosphatase 1 regulatory subunit 32.	Coiled-coil domain-containing protein 181 isoform X1.	0.516
PPP1R32	ENSVVUP00000000110	ENSVVUP00000006324	ENSVVUP00000000110	Protein phosphatase 1 regulatory subunit 32.	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial-like.	0.477