close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBA5Ubiquitin-like modifier-activating enzyme 5 isoform X1. (404 aa)    
Predicted Functional Partners:
UFC1
Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
  
 
 
 0.980
UFM1
Ubiquitin-fold modifier 1 isoform X2.
   
 
 0.978
GABARAPL2
Gamma-aminobutyric acid receptor-associated protein-like 2.
   
 0.909
UFL1
E3 UFM1-protein ligase 1.
   
 
 0.866
BIRC6
Baculoviral IAP repeat-containing protein 6 isoform X3.
   
 0.837
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X2.
    
 0.833
UBE2V1
Ubiquitin-conjugating enzyme E2 variant 1 isoform X3.
   
 
 0.829
UBE2F
NEDD8-conjugating enzyme UBE2F; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.783
UBE2M
NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.783
UFSP2
Ufm1-specific protease 2.
      
 0.758
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.