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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (495 aa)    
Predicted Functional Partners:
BICD2
Protein bicaudal D homolog 2 isoform X1.
    
 0.991
DYNC1I1
Cytoplasmic dynein 1 intermediate chain 1 isoform X2.
   
 0.991
DCTN1
Dynactin subunit 1 isoform X6.
   
 0.981
DYNC1I2
Cytoplasmic dynein 1 intermediate chain 2 isoform X5.
   
 0.975
HOOK3
Protein Hook homolog 3 isoform X2.
    
 0.910
DCTN6
Dynactin subunit 6.
    
 0.910
BICD1
Protein bicaudal D homolog 1 isoform X1.
    
 0.881
DCTN4
Dynactin subunit 4 isoform X1.
   
 0.880
PAFAH1B1
Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]
   
 0.878
DYNLL2
Dynein light chain.
    
 0.877
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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