STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FASNFatty acid synthase. (2516 aa)    
Predicted Functional Partners:
ACLY
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
   
 0.987
MCAT
malonyl-CoA-acyl carrier protein transacylase, mitochondrial.
  
 0.979
ACACB
acetyl-CoA carboxylase 2 isoform X1.
  
 
 0.966
ACACA
acetyl-CoA carboxylase 1 isoform X3.
  
 
 0.966
AASDH
Beta-alanine-activating enzyme isoform X1.
  
 0.964
AASDHPPT
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase.
   
 0.963
MECR
Enoyl-[acyl-carrier-protein] reductase, mitochondrial isoform X1.
  
 0.958
ACSF3
acyl-CoA synthetase family member 3, mitochondrial isoform X1.
  
 0.954
OXSM
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
0.949
ACSL3
long-chain-fatty-acid--CoA ligase 3.
  
 0.946
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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