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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLRD1Natural killer cells antigen CD94. (153 aa)    
Predicted Functional Partners:
TYROBP
TYRO protein tyrosine kinase-binding protein isoform X1.
   
 0.966
LOC112912180
HLA class I histocompatibility antigen, A-11 alpha chain-like isoform X1; Belongs to the MHC class I family.
    
 0.953
ENSVVUP00000018614
DLA class I histocompatibility antigen, A9/A9 alpha chain-like.
    
 0.946
LOC112913727
DLA class I histocompatibility antigen, A9/A9 alpha chain; Belongs to the MHC class I family.
    
 0.946
LOC112913586
DLA class I histocompatibility antigen, A9/A9 alpha chain-like isoform X2; Belongs to the MHC class I family.
    
 0.946
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.917
LOC112917497
LOW QUALITY PROTEIN: NKG2-A/NKG2-B type II integral membrane protein-like.
   
0.899
LOC112917500
NKG2-A/NKG2-B type II integral membrane protein-like.
   
 0.899
NKG7
Protein NKG7.
   
 
 0.827
GZMA
Granzyme A; Belongs to the peptidase S1 family.
   
 0.803
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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