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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCAR2Cell cycle and apoptosis regulator protein 2 isoform X1. (918 aa)    
Predicted Functional Partners:
SIRT1
NAD-dependent protein deacetylase sirtuin-1.
    
 0.889
RANBP3
Ran-binding protein 3 isoform X1.
   
    0.797
TMBIM6
Bax inhibitor 1; Belongs to the BI1 family.
      
 0.709
EDC4
Enhancer of mRNA-decapping protein 4.
   
    0.652
RBM39
RNA-binding protein 39 isoform X1.
   
 0.614
PSMB10
Proteasome subunit beta.
    
 
 0.604
HAO1
Hydroxyacid oxidase 1.
    
   0.595
TRIM56
E3 ubiquitin-protein ligase TRIM56.
    
 
 0.551
RNF40
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
    0.548
DDX46
Probable ATP-dependent RNA helicase DDX46 isoform X1.
   
 0.541
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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