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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AREL1Apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1. (823 aa)    
Predicted Functional Partners:
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X2.
   
 
0.720
VRTN
Vertnin.
      
 0.631
COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
      
 0.621
YLPM1
YLP motif-containing protein 1 isoform X1.
   
  
 0.620
ABCD4
ATP-binding cassette sub-family D member 4 isoform X1.
    
 
 0.615
LRRC74A
Leucine-rich repeat-containing protein 74A.
      
 0.605
FAM161B
Protein FAM161B.
      
 0.605
PROX2
LOW QUALITY PROTEIN: prospero homeobox protein 2.
      
 0.605
HEATR4
HEAT repeat-containing protein 4.
      
 0.603
SYNDIG1L
Synapse differentiation-inducing gene protein 1-like.
      
 0.603
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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