close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD6T-cell differentiation antigen CD6. (628 aa)    
Predicted Functional Partners:
CD5
T-cell surface glycoprotein CD5.
   
 
 0.916
ALCAM
CD166 antigen isoform X1.
    
 0.872
CD2
T-cell surface antigen CD2.
   
 0.820
CD4
T-cell surface glycoprotein CD4.
   
  
 0.750
CD3E
T-cell surface glycoprotein CD3 epsilon chain.
   
 
 0.724
ITK
Tyrosine-protein kinase.
   
 0.723
CD247
CD247 molecule.
   
 
 0.716
CD3G
T-cell surface glycoprotein CD3 gamma chain.
   
 
 0.645
SH2D1A
SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.
   
 0.616
CD7
T-cell antigen CD7.
   
  
 0.597
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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