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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCLRE1CProtein artemis isoform X2. (654 aa)    
Predicted Functional Partners:
XRCC5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
  
 0.980
PRKDC
DNA-dependent protein kinase catalytic subunit isoform X2; Belongs to the PI3/PI4-kinase family.
    
 0.958
XRCC6
LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 6.
   
 0.863
ENSVVUP00000024782
annotation not available
   
 0.863
ENSVVUP00000040346
annotation not available
   
 0.863
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.825
CPSF1
Cleavage and polyadenylation specificity factor subunit 1.
   
 0.822
SYMPK
Symplekin.
   
 0.804
FIP1L1
pre-mRNA 3'-end-processing factor FIP1 isoform X1.
    
 0.774
PCF11
pre-mRNA cleavage complex 2 protein Pcf11 isoform X1.
   
 0.740
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.