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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRBD1S1 RNA-binding domain-containing protein 1 isoform X1. (1005 aa)    
Predicted Functional Partners:
IWS1
Protein IWS1 homolog.
   
 0.900
LEO1
RNA polymerase-associated protein LEO1.
   
 0.894
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.876
SUPT16H
FACT complex subunit SPT16.
   
 0.873
CAMKMT
Calmodulin-lysine N-methyltransferase isoform X2.
      
 0.824
SUPT4H1
Transcription elongation factor SPT4.
    
 0.783
CDC73
Parafibromin isoform X1.
   
 0.743
POLR2G
DNA-directed RNA polymerase II subunit RPB7 isoform X2.
    
 0.743
POLR2E
DNA-directed RNA polymerases I, II, and III subunit RPABC1.
    
 0.737
RTF1
RNA polymerase-associated protein RTF1 homolog.
   
 
 0.725
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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