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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF9Rho guanine nucleotide exchange factor 9 isoform X4. (553 aa)    
Predicted Functional Partners:
GABRA2
Gamma-aminobutyric acid receptor subunit alpha-2 isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
 
 0.926
ARHGEF39
Rho guanine nucleotide exchange factor 39.
    
 0.815
ENSVVUP00000007132
annotation not available
    
 0.757
ENSVVUP00000019958
annotation not available
    
 0.757
CDC42
Cell division control protein 42 homolog isoform X2.
    
 0.757
GPHN
Gephyrin isoform X2.
   
 
 0.754
ARHGEF19
Rho guanine nucleotide exchange factor 19 isoform X1.
   
 
 0.747
ARHGEF2
Rho guanine nucleotide exchange factor 2 isoform X3.
   
 
 0.731
CHD1L
chromodomain-helicase-DNA-binding protein 1-like isoform X1.
    
 
 0.622
NLGN2
LOW QUALITY PROTEIN: neuroligin-2.
   
  
 0.612
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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