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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGD3FYVE, RhoGEF and PH domain-containing protein 3. (817 aa)    
Predicted Functional Partners:
CDC42
Cell division control protein 42 homolog isoform X2.
   
 0.940
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
 0.906
FGD1
FYVE, RhoGEF and PH domain-containing protein 1 isoform X1.
     
0.904
GNG14
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
  0.900
NOC3L
Nucleolar complex protein 3 homolog.
      
 0.702
TCEA2
Transcription elongation factor A protein 2 isoform X2.
      
 0.635
GIGYF1
GRB10-interacting GYF protein 1 isoform X3.
      
 0.607
TLCD3B
Protein FAM57B.
      
 0.607
EPB41L4A
Band 4.1-like protein 4A.
      
 0.606
CORO1A
Coronin; Belongs to the WD repeat coronin family.
   
  
 0.563
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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