TF protein (Vulpes vulpes) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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[Homology]

Score

TF

Serotransferrin-like; Belongs to the transferrin family. (756 aa)

Predicted Functional Partners:

TFRC

0.991

TF-2

0.901

TFR2

0.823

AHSG

0.656

ALB

0.599

EPO

0.575

LOC112929485

0.521

TTR

0.519

KCTD4

0.514

GC

0.503

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHSG	ALB	ENSVVUP00000017937	ENSVVUP00000020002	alpha-2-HS-glycoprotein.	Serum albumin.	0.940
AHSG	GC	ENSVVUP00000017937	ENSVVUP00000031492	alpha-2-HS-glycoprotein.	Vitamin D-binding protein.	0.861
AHSG	LOC112929485	ENSVVUP00000017937	ENSVVUP00000023838	alpha-2-HS-glycoprotein.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.605
AHSG	TF	ENSVVUP00000017937	ENSVVUP00000007516	alpha-2-HS-glycoprotein.	Serotransferrin-like; Belongs to the transferrin family.	0.656
AHSG	TF-2	ENSVVUP00000017937	ENSVVUP00000007494	alpha-2-HS-glycoprotein.	Serotransferrin isoform X2; Belongs to the transferrin family.	0.656
AHSG	TTR	ENSVVUP00000017937	ENSVVUP00000038373	alpha-2-HS-glycoprotein.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	0.702
ALB	AHSG	ENSVVUP00000020002	ENSVVUP00000017937	Serum albumin.	alpha-2-HS-glycoprotein.	0.940
ALB	EPO	ENSVVUP00000020002	ENSVVUP00000032357	Serum albumin.	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	0.578
ALB	GC	ENSVVUP00000020002	ENSVVUP00000031492	Serum albumin.	Vitamin D-binding protein.	0.604
ALB	LOC112929485	ENSVVUP00000020002	ENSVVUP00000023838	Serum albumin.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.834
ALB	TF	ENSVVUP00000020002	ENSVVUP00000007516	Serum albumin.	Serotransferrin-like; Belongs to the transferrin family.	0.599
ALB	TF-2	ENSVVUP00000020002	ENSVVUP00000007494	Serum albumin.	Serotransferrin isoform X2; Belongs to the transferrin family.	0.599
ALB	TFRC	ENSVVUP00000020002	ENSVVUP00000011445	Serum albumin.	Transferrin receptor protein 1.	0.638
ALB	TTR	ENSVVUP00000020002	ENSVVUP00000038373	Serum albumin.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	0.732
EPO	ALB	ENSVVUP00000032357	ENSVVUP00000020002	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Serum albumin.	0.578
EPO	TF	ENSVVUP00000032357	ENSVVUP00000007516	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Serotransferrin-like; Belongs to the transferrin family.	0.575
EPO	TF-2	ENSVVUP00000032357	ENSVVUP00000007494	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Serotransferrin isoform X2; Belongs to the transferrin family.	0.575
EPO	TFRC	ENSVVUP00000032357	ENSVVUP00000011445	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Transferrin receptor protein 1.	0.459
GC	AHSG	ENSVVUP00000031492	ENSVVUP00000017937	Vitamin D-binding protein.	alpha-2-HS-glycoprotein.	0.861
GC	ALB	ENSVVUP00000031492	ENSVVUP00000020002	Vitamin D-binding protein.	Serum albumin.	0.604