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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC112912331Phosphoinositide phospholipase C. (690 aa)    
Predicted Functional Partners:
SYK
Tyrosine-protein kinase.
   
0.992
BTK
Tyrosine-protein kinase.
   
 0.982
PDGFRB
Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
    
 0.978
LAT
Linker for activation of T-cells family member 1.
    
 0.976
BLNK
B-cell linker protein isoform X1.
   
 0.973
EGFR
Receptor protein-tyrosine kinase.
    
 0.967
VAV1
Proto-oncogene vav.
   
0.966
FGFR1
Fibroblast growth factor receptor.
    
 0.961
VAV3
Guanine nucleotide exchange factor VAV3 isoform X2.
   
0.955
NTRK2
Tyrosine-protein kinase receptor.
    
 0.955
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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