close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM12Disintegrin and metalloproteinase domain-containing protein 12. (897 aa)    
Predicted Functional Partners:
SH3PXD2A
SH3 and PX domain-containing protein 2A isoform X1.
    
 0.569
MMP9
Matrix metalloproteinase-9.
   
  
 0.542
ITGA11
Integrin alpha-11; Belongs to the integrin alpha chain family.
      
 0.514
VWCE
Von Willebrand factor C and EGF domain-containing protein isoform X1.
      
 0.467
POMGNT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2.
   
  
 0.445
TIMP3
Metalloproteinase inhibitor 3.
   
  
 0.445
PAPPA
Pappalysin-1.
      
 0.440
ADAM17
Disintegrin and metalloproteinase domain-containing protein 17.
      
0.438
HBEGF
Proheparin-binding EGF-like growth factor.
      
 0.438
GRB2
Growth factor receptor-bound protein 2.
    
 
 0.434
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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