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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1764 aa)    
Predicted Functional Partners:
UNC79
Protein unc-79 homolog isoform X5.
   
 0.922
SCN1B
Sodium channel subunit beta-1.
   
 0.745
KCNS2
Potassium voltage-gated channel subfamily S member 2; Belongs to the potassium channel family.
    
 
 0.740
SCN2B
Sodium channel subunit beta-2.
   
 0.675
PDE11A
Phosphodiesterase.
      
 0.629
SCN3B
Sodium channel subunit beta-3 isoform X2.
    
 0.624
WDR35
WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking.
    
 0.581
IFT122
Intraflagellar transport protein 122 homolog.
   
 0.573
CACNB3
Voltage-dependent L-type calcium channel subunit beta-3 isoform X2.
   
 0.567
SCN4B
Sodium channel subunit beta-4.
    
 0.566
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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