close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT2RAC-beta serine/threonine-protein kinase. (557 aa)    
Predicted Functional Partners:
PDPK1
3-phosphoinositide-dependent protein kinase 1 isoform X1.
  
0.985
FOXO1
Forkhead box protein O1.
    
 0.979
TSC1
Hamartin isoform X1.
    
 0.975
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.972
FOXO6
Forkhead box protein O6.
    
 0.970
FOXO3
Forkhead box protein O3.
    
 0.970
FOXO4
Forkhead box protein O4.
    
 0.970
TRIB3
Tribbles homolog 3.
   
0.969
CHUK
Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.
   
0.969
AKT1S1
Proline-rich AKT1 substrate 1 isoform X1.
   
 0.963
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.