PALB2 protein (Vulpes vulpes) - STRING interaction network

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Score

PALB2

Partner and localizer of BRCA2 isoform X2. (1301 aa)

Predicted Functional Partners:

BRCA2

0.998

BRCA1

0.992

NDUFB5

0.983

AASDH

0.981

NDUFB10

0.978

NDUFB9

0.978

MCAT

0.977

NDUFB4

0.976

NDUFC2

0.976

NDUFA12

0.974

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AASDH	MCAT	ENSVVUP00000008016	ENSVVUP00000001148	Beta-alanine-activating enzyme isoform X1.	malonyl-CoA-acyl carrier protein transacylase, mitochondrial.	0.526
AASDH	PALB2	ENSVVUP00000008016	ENSVVUP00000007967	Beta-alanine-activating enzyme isoform X1.	Partner and localizer of BRCA2 isoform X2.	0.981
BRCA1	BRCA2	ENSVVUP00000033145	ENSVVUP00000036965	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Breast cancer type 2 susceptibility protein.	0.999
BRCA1	PALB2	ENSVVUP00000033145	ENSVVUP00000007967	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Partner and localizer of BRCA2 isoform X2.	0.992
BRCA2	BRCA1	ENSVVUP00000036965	ENSVVUP00000033145	Breast cancer type 2 susceptibility protein.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.999
BRCA2	PALB2	ENSVVUP00000036965	ENSVVUP00000007967	Breast cancer type 2 susceptibility protein.	Partner and localizer of BRCA2 isoform X2.	0.998
MCAT	AASDH	ENSVVUP00000001148	ENSVVUP00000008016	malonyl-CoA-acyl carrier protein transacylase, mitochondrial.	Beta-alanine-activating enzyme isoform X1.	0.526
MCAT	PALB2	ENSVVUP00000001148	ENSVVUP00000007967	malonyl-CoA-acyl carrier protein transacylase, mitochondrial.	Partner and localizer of BRCA2 isoform X2.	0.977
NDUFA12	NDUFB10	ENSVVUP00000026170	ENSVVUP00000013317	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10.	0.999
NDUFA12	NDUFB4	ENSVVUP00000026170	ENSVVUP00000030550	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4.	0.999
NDUFA12	NDUFB5	ENSVVUP00000026170	ENSVVUP00000006222	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial.	0.999
NDUFA12	NDUFB9	ENSVVUP00000026170	ENSVVUP00000022971	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Belongs to the complex I LYR family.	0.999
NDUFA12	NDUFC2	ENSVVUP00000026170	ENSVVUP00000031441	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.999
NDUFA12	PALB2	ENSVVUP00000026170	ENSVVUP00000007967	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	Partner and localizer of BRCA2 isoform X2.	0.974
NDUFB10	NDUFA12	ENSVVUP00000013317	ENSVVUP00000026170	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10.	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.999
NDUFB10	NDUFB4	ENSVVUP00000013317	ENSVVUP00000030550	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4.	0.999
NDUFB10	NDUFB5	ENSVVUP00000013317	ENSVVUP00000006222	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial.	0.999
NDUFB10	NDUFB9	ENSVVUP00000013317	ENSVVUP00000022971	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10.	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Belongs to the complex I LYR family.	0.999
NDUFB10	NDUFC2	ENSVVUP00000013317	ENSVVUP00000031441	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10.	NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.999
NDUFB10	PALB2	ENSVVUP00000013317	ENSVVUP00000007967	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10.	Partner and localizer of BRCA2 isoform X2.	0.978