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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NTRK1Tyrosine-protein kinase receptor. (967 aa)    
Predicted Functional Partners:
NTF3
Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.
    
 0.816
NTF4
Neurotrophin-4; Belongs to the NGF-beta family.
    
 0.816
IRS2
LOW QUALITY PROTEIN: insulin receptor substrate 2.
    
 0.800
IRS1
Insulin receptor substrate 1.
    
 0.800
PTPRF
Receptor-type tyrosine-protein phosphatase F isoform X8.
   
 0.696
PTPRS
LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase S.
   
 0.696
PTPRD
Receptor-type tyrosine-protein phosphatase delta isoform X1.
   
 0.696
NGFR
Tumor necrosis factor receptor superfamily member 16.
   
 0.678
FRS2
Fibroblast growth factor receptor substrate 2 isoform X1.
    
 0.675
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.673
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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