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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM163Transmembrane protein 163. (233 aa)    
Predicted Functional Partners:
KHDRBS3
KH domain-containing, RNA-binding, signal transduction-associated protein 3.
      
 0.708
VRK1
Serine/threonine-protein kinase VRK1 isoform X2; Belongs to the protein kinase superfamily.
      
 0.603
KCNE2
Potassium voltage-gated channel subfamily E member 2.
      
 0.550
SLC22A3
Solute carrier family 22 member 3.
      
 0.538
QPCTL
Glutaminyl-peptide cyclotransferase-like protein isoform X2.
      
 0.516
CACNB2
Voltage-dependent L-type calcium channel subunit beta-2 isoform X4.
      
 0.499
KCTD15
BTB/POZ domain-containing protein KCTD15.
      
 0.450
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.