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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG2Pleckstrin homology domain-containing family G member 2 isoform X1. (1387 aa)    
Predicted Functional Partners:
LOC112914774
Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1.
    
 0.609
LOC112928570
Uncharacterized protein LOC112928570.
      
 0.605
LGI4
Leucine-rich repeat LGI family member 4.
      
 0.565
LOC112932169
Neuroendocrine secretory protein 55.
   
 0.495
SUPT5H
Transcription elongation factor SPT5.
    
 0.468
PLCE1
Phosphoinositide phospholipase C.
      
 0.453
ENSVVUP00000016164
annotation not available
  
 
  0.423
PPP1R3F
Protein phosphatase 1 regulatory subunit 3F isoform X1.
  
 
   0.413
TMEM190
Transmembrane protein 190.
  
     0.406
ARHGEF1
Rho guanine nucleotide exchange factor 1 isoform X3.
   
0.404
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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