Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPR180Integral membrane protein GPR180 isoform X1. (440 aa)    
Predicted Functional Partners:
LDLRAD4
Low-density lipoprotein receptor class A domain-containing protein 4.
      
 0.718
TMEM161A
Transmembrane protein 161A isoform X2.
      
 0.693
TGDS
dTDP-D-glucose 4,6-dehydratase.
   
  
 0.658
TMEM181
Transmembrane protein 181.
      
 0.614
SGCA
Alpha-sarcoglycan.
    
   0.586
GPR176
G-protein coupled receptor 176.
      
 0.575
GPR146
Probable G-protein coupled receptor 146 isoform X1.
      
 0.477
LOC112928735
Olfactory receptor.
      
 0.469
OR2AT4
Olfactory receptor.
      
 0.469
LOC112928736
Olfactory receptor.
      
 0.469
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.