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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF2RCation-independent mannose-6-phosphate receptor. (2518 aa)    
Predicted Functional Partners:
IGF2
Insulin-like growth factor II isoform X2.
    
 
 0.998
M6PR
Cation-dependent mannose-6-phosphate receptor.
     
 0.996
GGA1
ADP-ribosylation factor-binding protein GGA1.
    
 
 0.935
GAK
cyclin-G-associated kinase isoform X3.
   
 0.932
GGA3
ADP-ribosylation factor-binding protein GGA3.
    
 
 0.931
IGF1
Insulin-like growth factor I isoform X1.
      
 0.898
IGF1R
Tyrosine-protein kinase receptor.
   
 
 0.832
GGA2
ADP-ribosylation factor-binding protein GGA2.
    
 
 0.789
SORL1
Sortilin-related receptor.
    
 0.784
SNX1
Sorting nexin-1 isoform X2.
    
 0.778
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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