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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELZProbable helicase with zinc finger domain isoform X1. (1945 aa)    
Predicted Functional Partners:
CNOT1
CCR4-NOT transcription complex subunit 1 isoform X1.
   
 
 0.809
RC3H2
Roquin-2 isoform X1.
   
 
 0.801
ATXN2L
Ataxin-2-like protein.
   
 
 0.768
OPTC
Opticin.
      
 0.732
PITPNC1
Cytoplasmic phosphatidylinositol transfer protein 1 isoform X1.
      
 0.714
KMT2E
LOW QUALITY PROTEIN: inactive histone-lysine N-methyltransferase 2E.
   
 
 0.636
MAP3K2
Mitogen-activated protein kinase kinase kinase 2 isoform X2.
   
 
 0.618
CSTF2T
Cleavage stimulation factor subunit 2 tau variant.
    
 
 0.611
DEAF1
Deformed epidermal autoregulatory factor 1 homolog isoform X1.
      
 0.607
PATL2
Protein PAT1 homolog 2.
    
 
 0.591
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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