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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDM5BLysine-specific demethylase 5B. (1483 aa)    
Predicted Functional Partners:
ATP5F1C
ATP synthase subunit gamma.
  
 0.891
ATP5F1D
ATP synthase subunit delta, mitochondrial.
  
 0.891
ATP5PO
ATP synthase subunit O, mitochondrial.
  
 0.820
ENSVVUP00000040510
annotation not available
  
 0.820
TFAP2C
Transcription factor AP-2 gamma.
   
 0.795
ENSVVUP00000002733
annotation not available
  
 0.773
ENSVVUP00000030107
annotation not available
  
 0.773
ATP6
ATP synthase subunit a.
  
 0.773
ATP5F1E
ATP synthase subunit epsilon, mitochondrial.
    
 0.750
ENSVVUP00000010893
annotation not available
  
 0.739
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.