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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP3S2AP-3 complex subunit sigma-2 isoform X1. (193 aa)    
Predicted Functional Partners:
AP3D1
AP-3 complex subunit delta-1 isoform X1.
    
 0.990
AP3M1
AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
   
 0.985
AP3B1
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.978
AP3M2
AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family.
   
 0.963
AP3S1
AP-3 complex subunit sigma-1.
  
  
 
0.901
GAK
cyclin-G-associated kinase isoform X3.
   
 0.875
AP1G2
AP-1 complex subunit gamma.
    
 0.864
AP3B2
AP-3 complex subunit beta.
    
 0.862
AP4E1
AP-4 complex subunit epsilon-1.
    
 0.859
AP2A1
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 0.851
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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