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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GM2AGanglioside GM2 activator. (196 aa)    
Predicted Functional Partners:
HEXB
Beta-hexosaminidase subunit beta.
    
 0.923
HEXA
Beta-hexosaminidase.
    
 0.893
MEP1B
Meprin A subunit.
      
 0.670
TLR3
Toll-like receptor 3 isoform X2; Belongs to the Toll-like receptor family.
      
 0.621
MRPS10
28S ribosomal protein S10, mitochondrial.
   
  
 0.616
HAO2
Hydroxyacid oxidase 2 isoform X2.
   
  
 0.611
B3GALT4
Hexosyltransferase.
      
 0.604
HPGD
15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.579
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
      
 0.569
UGP2
UTP--glucose-1-phosphate uridylyltransferase.
      
 0.564
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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