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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM120BConstitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X2. (1022 aa)    
Predicted Functional Partners:
PDCD2
Programmed cell death protein 2.
      
 0.776
PSMB7
Proteasome subunit beta.
    
 0.716
PALB2
Partner and localizer of BRCA2 isoform X2.
    
 0.621
PSMB1
Proteasome subunit beta.
    
 0.611
ENSVVUP00000014607
annotation not available
    
 0.611
ARID4B
LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 4B.
    
 0.607
NSMCE1
Non-structural maintenance of chromosomes element 1 homolog.
      
 0.605
FANCM
Fanconi anemia group M protein.
   
 0.553
POLD2
DNA polymerase delta subunit 2.
    
 0.543
TOP3A
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 
 0.529
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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