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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARLPresenilins-associated rhomboid-like protein, mitochondrial. (379 aa)    
Predicted Functional Partners:
STOML2
Stomatin-like protein 2, mitochondrial.
   
 0.860
YME1L1
ATP-dependent zinc metalloprotease YME1L1 isoform X1.
   
 
 0.795
RHBDL1
Rhomboid-related protein 1 isoform X1; Belongs to the peptidase S54 family.
      
 0.776
PINK1
Serine/threonine-protein kinase PINK1, mitochondrial.
    
 
 0.763
RHBDL2
LOW QUALITY PROTEIN: rhomboid-related protein 2; Belongs to the peptidase S54 family.
      
 0.728
AFG3L2
AFG3-like protein 2 isoform X1.
   
 
 0.690
PMPCB
Mitochondrial-processing peptidase subunit beta; Belongs to the peptidase M16 family.
   
  
 0.641
PRKN
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
    
 
 0.619
PRKN-2
E3 ubiquitin-protein ligase parkin.
    
 
 0.619
OMA1
Metalloendopeptidase OMA1, mitochondrial isoform X1.
    
 
 0.618
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.