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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (446 aa)    
Predicted Functional Partners:
MAPK1
Mitogen-activated protein kinase.
  
0.935
MAPK3
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
  
0.935
MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily.
  
  
 
0.903
ATF4
Cyclic AMP-dependent transcription factor ATF-4.
     
 0.901
LOC112916519
Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family.
     
  0.900
EIF4E2
Eukaryotic translation initiation factor 4E type 2 isoform X1; Belongs to the eukaryotic initiation factor 4E family.
     
  0.900
LURAP1
Leucine rich adaptor protein 1.
      
 0.603
AHCYL2
Adenosylhomocysteinase.
   
  
 0.483
MAP3K11
Mitogen-activated protein kinase kinase kinase.
   
 
0.471
RASA2
Ras GTPase-activating protein 2 isoform X4.
      
 0.461
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.