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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM150BModulator of macroautophagy TMEM150B. (202 aa)    
Predicted Functional Partners:
LRRC61
Leucine-rich repeat-containing protein 61.
      
 0.775
ZCCHC2
Zinc finger CCHC domain-containing protein 2.
      
 0.607
ZNF518A
Zinc finger protein 518A.
      
 0.607
BLK
Tyrosine-protein kinase.
   
  
 0.605
GPR12
G-protein coupled receptor 12; Belongs to the G-protein coupled receptor 1 family.
      
 0.545
HMCES
Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]
      
 0.516
UIMC1
Ubiquitin interaction motif containing 1.
      
 0.497
CAB39L
Calcium-binding protein 39-like.
      
 0.438
ODAM
Odontogenic ameloblast-associated protein.
      
 0.436
WASHC3
WASH complex subunit 3 isoform X2.
   
  
 0.418
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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