PAX4 protein (Vulpes vulpes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

PAX4

LOW QUALITY PROTEIN: paired box protein Pax-4. (345 aa)

Predicted Functional Partners:

INS

0.821

SUZ12

0.779

SP3

0.757

TIMM22

0.754

PCSK1

0.721

SLC30A8

0.716

NEUROG2

0.704

NEUROG3

0.704

TIMM10

0.661

NEUROD2

0.659

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
INS	NEUROD2	ENSVVUP00000003455	ENSVVUP00000001802	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenic differentiation factor.	0.548
INS	NEUROG2	ENSVVUP00000003455	ENSVVUP00000002765	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	LOW QUALITY PROTEIN: neurogenin-2.	0.561
INS	NEUROG3	ENSVVUP00000003455	ENSVVUP00000029500	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenin-3.	0.561
INS	PAX4	ENSVVUP00000003455	ENSVVUP00000009753	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	LOW QUALITY PROTEIN: paired box protein Pax-4.	0.821
INS	PCSK1	ENSVVUP00000003455	ENSVVUP00000029813	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neuroendocrine convertase 1 isoform X2; Belongs to the peptidase S8 family.	0.818
INS	SLC30A8	ENSVVUP00000003455	ENSVVUP00000020882	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Zinc transporter 8 isoform X1.	0.700
NEUROD2	INS	ENSVVUP00000001802	ENSVVUP00000003455	Neurogenic differentiation factor.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.548
NEUROD2	PAX4	ENSVVUP00000001802	ENSVVUP00000009753	Neurogenic differentiation factor.	LOW QUALITY PROTEIN: paired box protein Pax-4.	0.659
NEUROD2	PCSK1	ENSVVUP00000001802	ENSVVUP00000029813	Neurogenic differentiation factor.	Neuroendocrine convertase 1 isoform X2; Belongs to the peptidase S8 family.	0.469
NEUROD2	SLC30A8	ENSVVUP00000001802	ENSVVUP00000020882	Neurogenic differentiation factor.	Zinc transporter 8 isoform X1.	0.418
NEUROG2	INS	ENSVVUP00000002765	ENSVVUP00000003455	LOW QUALITY PROTEIN: neurogenin-2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.561
NEUROG2	PAX4	ENSVVUP00000002765	ENSVVUP00000009753	LOW QUALITY PROTEIN: neurogenin-2.	LOW QUALITY PROTEIN: paired box protein Pax-4.	0.704
NEUROG2	PCSK1	ENSVVUP00000002765	ENSVVUP00000029813	LOW QUALITY PROTEIN: neurogenin-2.	Neuroendocrine convertase 1 isoform X2; Belongs to the peptidase S8 family.	0.461
NEUROG3	INS	ENSVVUP00000029500	ENSVVUP00000003455	Neurogenin-3.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.561
NEUROG3	PAX4	ENSVVUP00000029500	ENSVVUP00000009753	Neurogenin-3.	LOW QUALITY PROTEIN: paired box protein Pax-4.	0.704
NEUROG3	PCSK1	ENSVVUP00000029500	ENSVVUP00000029813	Neurogenin-3.	Neuroendocrine convertase 1 isoform X2; Belongs to the peptidase S8 family.	0.461
PAX4	INS	ENSVVUP00000009753	ENSVVUP00000003455	LOW QUALITY PROTEIN: paired box protein Pax-4.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.821
PAX4	NEUROD2	ENSVVUP00000009753	ENSVVUP00000001802	LOW QUALITY PROTEIN: paired box protein Pax-4.	Neurogenic differentiation factor.	0.659
PAX4	NEUROG2	ENSVVUP00000009753	ENSVVUP00000002765	LOW QUALITY PROTEIN: paired box protein Pax-4.	LOW QUALITY PROTEIN: neurogenin-2.	0.704
PAX4	NEUROG3	ENSVVUP00000009753	ENSVVUP00000029500	LOW QUALITY PROTEIN: paired box protein Pax-4.	Neurogenin-3.	0.704