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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K21Mitogen-activated protein kinase kinase kinase 21. (871 aa)    
Predicted Functional Partners:
TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.
   
 0.591
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.579
MIB2
E3 ubiquitin-protein ligase MIB2 isoform X1.
   
 0.572
SGO1
Shugoshin 1.
   
 0.566
CD247
CD247 molecule.
   
 0.562
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2.
   
 0.541
FADD
FAS-associated death domain protein.
   
 0.525
MAP2K4
Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
   
0.517
DMWD
Dystrophia myotonica WD repeat-containing protein.
   
 0.495
TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.
    
 0.487
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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