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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (738 aa)    
Predicted Functional Partners:
AP4E1
AP-4 complex subunit epsilon-1.
   
 0.999
AP4M1
AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
   
 0.999
AP4S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.995
ITSN2
Intersectin-2 isoform X4.
    
 0.994
ENSVVUP00000013880
annotation not available
    
 0.958
AP1G2
AP-1 complex subunit gamma.
   
 0.947
ENSVVUP00000031532
annotation not available
    
 0.945
ITSN1
Intersectin-1 isoform X1.
    
 0.945
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.926
AP2A1
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
 0.924
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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