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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHOX2BPaired mesoderm homeobox protein 2B. (180 aa)    
Predicted Functional Partners:
TH
Tyrosine 3-monooxygenase isoform X1.
   
  
 0.853
GPR4
G-protein coupled receptor 4; Belongs to the G-protein coupled receptor 1 family.
      
 0.637
DBH
Dopamine beta-hydroxylase.
   
  
 0.633
HAND2
Heart- and neural crest derivatives-expressed protein 2.
   
 
 0.617
SOX10
Transcription factor SOX-10.
   
  
 0.607
MYCN
N-myc proto-oncogene protein.
      
 0.550
NMB
neuromedin-B isoform X1.
      
 0.528
SLC18A3
Vesicular acetylcholine transporter.
      
 0.527
ASCL1
Achaete-scute homolog 1.
   
 
 0.523
GATA3
Trans-acting T-cell-specific transcription factor GATA-3.
      
 0.521
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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