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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANK2Ankyrin-2. (731 aa)    
Predicted Functional Partners:
ITPR1-2
Inositol 1,4,5-trisphosphate receptor type 1.
    
 0.912
TIAM1
T-lymphoma invasion and metastasis-inducing protein 1 isoform X1.
    
 0.912
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
    
 0.909
ANK1
Ankyrin-1 isoform X2.
     
 
0.900
ENSVVUP00000011659
annotation not available
 
      0.900
ENSVVUP00000006889
annotation not available
 
      0.899
NFASC
Neurofascin isoform X3.
   
 0.804
RNF146
E3 ubiquitin-protein ligase RNF146.
    
 0.671
AXIN2
Axin-2 isoform X1.
    
 0.625
AXIN1
Axin-1 isoform X1.
    
 0.625
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.